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ANTI-HIF1ALPHA(C-TERMINAL) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1306172
规格纯度
purified immunoglobulin, buffered aqueous solution
参考价格
6662.67 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
ANTI-HIF1ALPHA(C-TERMINAL) antibody produced in rabbit
HIF1A
PASD8
Hypoxia-inducible factor 1-alpha
MOP1
bHLHe78
产品介绍:

产品说明

一般描述

Hypoxia-inducible factor-1 (HIF1) is a transcription factor expressed in mammalian cells when cultured under reduced oxygen tension. HIF1 is a heterodimer composed of an α subunit and a β subunit. The β subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. HIF-1α contains two transactivation domains. The gene encoding it is localized on human chromosome 14q23.2.

生化/生理作用

Hypoxia-inducible factor-1 (HIF1) plays an essential role in cellular and systemic homeostatic responses to hypoxia. During hypoxia, the two subunits of this factor undergo post-translational modifications, which in turn promote transactivation. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. HIF-1α is a master regulator of the hypoxic response, and its proangiogenic activities include, but are not limited to, regulation of vascular endothelial growth factor (VEGF).

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 92670 Da
species reactivitymouse, human
technique(s)immunofluorescence: 1:10-1:50
immunohistochemistry: 1:10-1:50
western blot: 1:1000
NCBI登记号NP_001230013.1
UniProt登记号Q16665
运输wet ice
储存温度−20℃
Gene Informationhuman ... HIF1A(3091)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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