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Anti-hnRNP A1 (Ab-192) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300651
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-hnRNP A1 (Ab-192) antibody produced in rabbit
Anti-hnRNP A1
Anti-hnRNP-A1
Anti-HNRPA1
Anti-MGC102835
Anti-HNRPA1L3
产品介绍:

产品说明

一般描述

The antibody detects endogenous levels of total hnRNP A1 protein.

免疫原

Peptide sequence around aa. 190-194 (S-S-S-Q-R), according to the protein NP_002127.1

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts . hnRNP A1 regulates the alternative splicing of c-Src, c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers; knockdown of hnRNP A1 leads to apoptosis in various cancer cells . Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus . hnRNP A1 binds to cis-acting repressive sequences (CRS) of HIV-1 to influence HIV-1 production . HIV-1 enhances hnRNP A1 expression and promotes the relocalization of hnRNP A1 to the cytoplasm ,

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 34-39 kDa
species reactivitymouse, rat, human
浓度1 mg/mL
technique(s)western blot: 1:500-1:1000
同位素/亚型IgG
免疫原序列(S-S-S-Q-R)
NCBI登记号NM_002136.2
运输wet ice
储存温度−20℃
Gene Informationhuman ... hnRNP A1(3178)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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