产品说明
一般描述
BRE1-A (E3 ubiquitin-protein ligase BRE1A) also known by it′s gene name hRNF20, plays a role in histone code and gene regulation as a component of the RNF20/40 E3 ubiquitin-protein ligase complex. That complex mediates monoubiquitination of ′Lys-120′ of histone H2B,which is a specific tag for epigenetic transcriptional activation as well as a prerequisite for histone H3 ′Lys-4′ (H3K4me) and ′Lys-79′ (H3K79me) methylation.
免疫原
GST-tagged recombinant protein corresponding to human hRNF20.
应用
This hRNF20 antibody is validated for use in WB for the detection of the hRNF20 protein.
质量
Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected hRNF20 in 10 µg of A431 cell lysate.
目标描述
~113 kDa observed
外形
Affinity purified
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 纯化方式 | affinity chromatography |
| species reactivity | mouse, human, rat |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_062538 |
| UniProt登记号 | Q5VTR2 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
