产品说明
一般描述
Heat shock protein family B, member 2 (HSPB2) is also called as myotonic dystrophy kinase binding protein (MKBP). It is expressed in the skeletal muscles and heart. Studies have also shown that HSPB2 is overexpressed in lung fibrosis. The gene encoding it is localized on human chromosome 11q22-q23. The gene ID of the protein is 3316.
特异性
Detects ~27 kDa.
免疫原
Synthetic peptide
生化/生理作用
Heat shock protein family B, member 2 (HSPB2) binds to ubiquitin and hydrogen peroxide-inducible clone 5, an adaptor protein. This association is important for the ubiquitination and degradation of NADPH oxidase 4 (Nox4). It is also crucial for the degradation of other proteins. HSPB2 interacts with myotonic dystrophy protein kinase (DMPK) and activates it.
特点和优势
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外形
PBS, 50% glycerol, and 0.02% sodium azide
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous glycerol solution |
| 分子量 | antigen predicted mol wt 27 kDa |
| species reactivity | human, rat, mouse |
| 浓度 | 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_001532.1 |
| UniProt登记号 | Q16082 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HSPB2(3316) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
