Anti-HTR3A

产品说明

一般描述

5-Hydroxytryptamine 3 receptor (HTR3A) belongs to a pentameric ligand gated channel receptor family. HTR3A is also called 5-HT3. Serotonin receptor type 3 (HTR3A) is encoded by two different subunit genes called HTR3A and HTR3B, which also has variants. Serotonin (5-hydroxytryptamine, 5-HT) is a bioamine derived from the amino acid tryptophan. HTR3A is located on human chromosome 11q23.2.

免疫原

Synthetic peptide directed towards the N terminal region of human HTR3A

应用

Anti-HTR3A produced in rabbit has been used in immunohistochemistry.

生化/生理作用

5-Hydroxytryptamine 3 receptor (HTR3A) induces neuronal excitation and neurotransmitter release in peripheral and central nervous systems. Messenger RNA encoding this receptor is localised in the brain, spinal cord, and heart. It also initiates intracellular signalling cascades. HRT3A can be used to treat alcoholic patients by regulating the H3K9 histone acetylation in HRT3A promoter region. HTR3A is linked to human colon cancer.

序列

Synthetic peptide located within the following region: LLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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