产品说明
一般描述
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
免疫原
A synthetic peptide of human IL6
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at 4℃. Avoid freeze / thaw cycles.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 23 |
species reactivity | human, rat |
浓度 | 1.8 mg/ml |
technique(s) | flow cytometry: 1:20-1:50 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:2000 |
UniProt登记号 | P05231 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... IL6(3569) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich