产品说明
一般描述
Interleukin-6 (IL6) is a multifunctional cytokine.
免疫原
recombinant human IL6
应用
Anti-IL6 high affinity antibody, Mouse monoclonal has been used in
生化/生理作用
Interleukin-6 (IL6) plays a wide variety of important biological roles in the immune, nervous and endocrine system. It is an essential component for hybridoma growth and is found in many supplemental cloning media. IL6 regulates acute and chronic inflammatory diseases and has been proven to be an excellent target for clinical treatment against autoimmune disorders such as rheumatoid arthritis, juvenile idiopathic arthritis and Castleman′s disease. IL6 also plays a key role in the pathogenesis of multiple myeloma.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | IL6-2A3, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | ELISA: suitable immunoblotting: 0.125-0.25 μg/mL using recombinant human IL6 expressed in HEK-293T cells immunoprecipitation (IP): 10-20 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β |
| 同位素/亚型 | IgG2a |
| UniProt登记号 | P05231 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IL6(3569) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
