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Anti-Insulin-degrading enzyme (IDE) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700928
包装型号
规格纯度
参考价格
4668.88 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Insulin-degrading enzyme (IDE) antibody produced in rabbit
产品介绍:

产品说明

一般描述

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009]

免疫原

A synthesized peptInsulin-degrading enzyme (Insulin-degrading enzyme (IDE)) derived from human Insulin-degrading enzyme (Insulin-degrading enzyme (IDE))

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivitymouse, rat, human
浓度0.5 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt登记号P14735
运输wet ice
储存温度−20℃
Gene Informationhuman ... IDE(3416)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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