Anti-ITLN1 antibody produced in rabbit

产品说明

一般描述

Omentin (intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. It is a plasma adipokine made up of 313 amino acids.

特异性

The antibody detects endogenous levels of total ITLN1 protein.

免疫原

Fusion protein corresponding to a region derived from internal residues of human intelectin 1 (galactofuranose binding)

生化/生理作用

Omentin (intelectin-1) has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases protein kinase B (AKT) phosphorylation in the absence and presence of insulin. Omentin was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues. It has anti-inflammatory and insulin-sensitizing properties. The protein may be a biomarker of metabolic disorders. It has been shown to be over-expressed in human malignant pleural mesothelioma (MPM).

特点和优势

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外形

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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