产品说明
一般描述
K-homology type-splicing regulatory protein (KHSRP) is a multifunctional RNA-binding protein. It contains four K homology RNA-binding domains and an unusual C-terminal domain. KHSRP is localized in neural and non-neural cell lines. It is located on the human chromosome at 19p13.3.
特异性
Anti-KHSRP recognizes human, mouse and rat KHSRP.
免疫原
synthetic peptide corresponding to an internal region of human KHSRP (GeneID: 8570), conjugated to KLH. The corresponding sequence is identical in rat, mouse, monkey, pig and dog KHSPR.
应用
Anti-KHSRP antibody produced in rabbit may be used in immunoblotting and immunoprecipitation.
生化/生理作用
K-homology type-splicing regulatory protein (KHSRP) is involved in several cellular processes such as transcription, mRNA localization and alternative pre-mRNA splicing. It is also involved in mRNA decay and microRNA precursor maturation.
外形
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
储存及稳定性
For continuous use, store at 2-8 ℃ for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen ~82 kDa |
species reactivity | rat, human, mouse |
浓度 | ~1.0 mg/mL |
technique(s) | immunoprecipitation (IP): 1-2 μg using lysates of human HEK-293T cells western blot: 0.25-0.50 μg/mL using whole extracts of mouse NIH-3T3 cells |
UniProt登记号 | Q92945 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... KHSRP(8570) mouse ... Khsrp(16549) rat ... Khsrp(171137) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich