产品说明
一般描述
The gene KIAA0196 (strumpellin) is mapped to human chromosome 8q24. It is a widely expressed gene and the protein localizes in the cytoplasm and endoplasmic reticulum.
免疫原
Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human Strumpellin.
生化/生理作用
KIAA0196 (strumpellin) is involved in the WASH (WASP and Scar homologue) complex, an actin-regulating complex. It works as an interlink between actin regulation and endosomal membrane dynamics. Mutations in KIAA0196 are associated with spastic paraplegia and RSS (Ritscher-Schinzel syndrome).
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
联系
The action of this antibody can be blocked using blocking peptide SBP3500640.
外形
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
分子量 | 127 kDa |
species reactivity | mouse, human, rat |
浓度 | 1 mg/mL |
technique(s) | ELISA: suitable western blot: suitable |
NCBI登记号 | NP_055661 |
UniProt登记号 | Q12768 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... KIAA0196(9897) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich