产品说明
一般描述
Mouse polyclonal antibody raised against a full-length human KIAA1456 protein. The gene KIAA1456 is mapped to human chromosome 8. It has an SAM (S-adenosyl methionine)-dependent methyltransferase domain.
免疫原
KIAA1456 (NP_065895, 1 a.a. ~ 367 a.a) full-length human protein.
Sequence
MVCDNLNLPFRDEGFDAIISIGVIHHFSTKQRRIRAIKEMARVLVPGGQLMIYVWAMEQKNRRFEKQDVLVPWNRALCSQLFSESSQSGRKRQCGYPERGHPYHPPCSECSCSVCFKEQGGSKRSHSVGYEPAMARTCFANISKEGEEEYGFYSTLGKSFRSWFFSRSLDESTLRKQIERVRPLKNTEVWASSTVTVQPSRHSSLDFDHQEPFSTKEQSLDEEVFVESSSGKHLEWLRAPGTLKHLNGDHQGEMRRNGGGNFLDSTNTGVNCVDAGNIEDDNPSASKILRRISAVDSTDFNPDDTMSVEDPQTDVLDSTAFMRYYHVFREGELCSLLKENVSELRILSSGNDHGNWCIIAEKKGGCD
生化/生理作用
KIAA1456 might be involved in the regulation of the translation of specific protein(s) via the methyltransferase activity. It negatively regulates tumor growth and the mRNA is downregulated in breast, bladder, colorectal, cervical and testicular carcinomas.
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen ~41.5 kDa |
species reactivity | human |
technique(s) | indirect immunofluorescence: suitable western blot: 1 μg/mL |
NCBI登记号 | NM_020844 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... C8orf79(57604) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich