Anti-KIF3A Antibody, clone 4F9.1

产品说明

一般描述

Kinesin-like protein KIF3A (UniProt Q9Y496; also known as Kinesin family protein 3A, Microtubule plus end-directed kinesin motor 3A) is encoded by the KIF3A (also known as FLA10, KIF3, KLP-20) gene (Gene ID 11127) in human. Kinesin-2 is a heterotrimeric motor protein composed of two kinesin-related subunits, KIF3A and KIF3B, and an associated protein KAP3. The kinesin-2 motor KIF3A/B drives intraflagellar transport (IFT) of tubulins and other axonemal building blocks in cilia and flagella, pigment granules in melanosomes, and vesicles in neurons. Defects in these transport processes are linked to polycystic kidney disease and neurodegenerative diseases.

免疫原

KLH-conjugated linear peptide corresponding to the C-terminal of human KIF3A.
Epitope: C-terminal

应用

This Anti-KIF3A Antibody, clone 4F9.1 is validated for use in Western Blotting and Immunohistochemistry for the detection of KIF3A.
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected KIF3A in 10 µg of rat hippocampus tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected KIF3A in human cerebellum and human cerebral cortex tissue.
Research Sub Category
Apoptosis - Additional
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in mouse cerebellum tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected KIF3A in 10 µg of mouse cerebellum tissue lysate.

目标描述

~75 kDa observed

外形

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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