产品说明
一般描述
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. KLHL1 contains one BTB (POZ) domain and six Klech repoeats. KLHL1 may play an important role in organizing the actin cytoskeleton of the brain cells. Mutations associated with KLHL1 are inplicated in spinocerebellar ataxia type 8 (SCA8).
免疫原
KLH-conjugated linear peptide corresponding to human KLHL1.
应用
Research Category
Cell Structure
Immunohistochemistry Analysis: 10 µg/mL from a representative lot detected KLHL1 in rat brain tissue.
Detect Kelch-like 1 using this rabbit polyclonal antibody, Anti-KLHL1 Antibody validated for use in western blotting & IHC.
Research Sub Category
Cytoskeleton
质量
Evaluated by Western Blotting in human brain tissue lysate.
Western Blotting Analysis: 4 µg/mL of this antibody detected KLHL1 in 15 µg/mL of human brain tissue lysate.
目标描述
~100 kDa observed
外形
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Human brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, rat |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | Q9NR64 |
运输 | wet ice |
Gene Information | human ... KLHL1(57626) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich