产品说明
一般描述
Left-right determination factor 1 (LEFTY1) also known as Left-right determination factor B, Protein lefty-1, Protein lefty-B, and encoded by the gene name LEFTYB, LEFTY1, LEFTB, is a member of the the TGF-beta family. LEFTY1 collaborates with other members of the TGFβ (Transforming Growth Factor) family to establish a left-right axis that dictates the asymmetrical distribution of internal organs during vertebrate embryogenesis. Mice deficient in LEFTY1 are affected by pulmonary isomerism and abnormal placement of vascular tracts, possibly the result of unregulated expression of LEFTY2 and NODAL.
免疫原
KLH-conjugated linear peptide corresponding to human Lefty and spans the pro and mature cleavage sites.
应用
Research Sub Category
Cell Cycle, DNA Replication & Repair
Anti-Lefty Antibody, clone 1G9.1 | MABD146 is an antibody against Lefty Antibody for use in Western Blotting.
Research Category
Stem Cell Research
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Lefty in 10 µg of C2C12 and NIH-3T3 cell lysate.
质量
Evaluated by Western Blotting in L6 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Lefty in 10 µg of L6 cell lysate.
目标描述
~40 kDa observed
联系
Replaces: MABD186
外形
Purified by Ion-Exchange Chromatography
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.75 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | 1G9.1, monoclonal |
species reactivity | rat, mouse |
technique(s) | western blot: suitable |
同位素/亚型 | IgMκ |
NCBI登记号 | NP_066277 |
UniProt登记号 | O75610 |
运输 | wet ice |
Gene Information | human ... LEFTY1(10637) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich