产品说明
一般描述
LHX8 codes for a LIM homeobox transcription factor that is involved in neuronal differentiation and tooth morphogenesis. LHX8 induces the neuronal expression of Shh that modulates the development of interneuronal progenitors. It also regulates the development of cholinergic neurons in mouse forebrain. It also functions as a germ cell-specific modulator of oogenesis.
Rabbit Anti-LHX8 antibody recognizes bovine, human, mouse, rat, canine, chicken, and pig LHX8.
免疫原
Synthetic peptide directed towards the middle region of human LHX8
应用
Rabbit Anti-LHX8 antibody is suitable for western blot applications at a concentration of 2.5 μg/ml.
生化/生理作用
LHX8 is a member of the LIM homeobox family. Members of this family share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other proteins. Members of the family are required for the patterning or the specification and differentiation of different cell types during embryonic development.
序列
Synthetic peptide located within the following region: LSTGEEFALVEEKVLCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVN
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 39 kDa |
| species reactivity | human, rat, horse, guinea pig, rabbit, bovine, dog, mouse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_001001933 |
| UniProt登记号 | Q68G74 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... LHX8(431707) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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