产品说明
一般描述
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget′s disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LITAF (NP_004853.2).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 15 17 23 |
| species reactivity | mouse, human |
| 浓度 | 2.05 mg/ml |
| technique(s) | immunohistochemistry: 1:50-1:200 immunoprecipitation (IP): 1:50-1:100 western blot: 1:500-1:2000 |
| UniProt登记号 | Q99732 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... LITAF(9516) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
