产品说明
一般描述
MAP1b is the major microtubule associated protein in developing brain which changes its expression during development. In the newborn rat brain, it is a major component of microtubules but in the adult its level is ten-fold lower.1 This change in the level of expression occurs simultaneously with neuronal maturation
特异性
Monoclonal Anti-MAP1b antibody is immunospecific for MAP1b (also known as MAP5, MAPIX or MAP1.2)1,2 Monoclonal Anti-MAP1b reacts with human, rat, mouse, bovine, hamster, chicken and cat tissue or cells. Monoclonal Anti-MAP1b does not react with tubulin of other microtubule associated proteins.
应用
The antibody may be used in various immunochemical techniques including immunohistology and Immunoblotting.
生化/生理作用
MAP1b is the first MAP to appear in growing axons during development as it is present from the first emergence of the nascent axon from the cell body.4
外形
Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.
储存及稳定性
For continuous use, store at 2-8℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免责声明
This product is for R&D use only, not for drug, household, or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.
产品性质
质量水平 | 200 |
抗体形式 | purified from hybridoma cell culture |
克隆 | AA6 |
形式 | liquid |
species reactivity | hamster, mouse, bovine, cat, rat, human |
增强验证 | functional assay Learn more about Antibody Enhanced Validation |
浓度 | ~1 mg/mL |
同位素/亚型 | IgG1 |
UniProt登记号 | P46821 |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich