Anti-MCM2 antibody, Rabbit monoclonal

产品说明

一般描述

Mini chromosome maintenance protein 2 (MCM2) is a human nuclear protein. This cell-cycle regulatory protein is similar to members of the family of early S-phase proteins and is expressed in four phases of the cell cycle. MCM2 gene is mapped to human chromosome 3q21.3. MCM2 protein is a member of eukaryal MCM2–7 subunits and is expressed in the nucleus and cytoplasm of various tissues.

免疫原

Synthetic peptide derived from internal region of human MCM2 protein.

生化/生理作用

Mini chromosome maintenance protein 2 (MCM2) is involved in regulating DNA replication, is crucial in the cell cycle. From its localization, CDCL1 is a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML). MCM-2 levels are elevated in salivary gland tumors and malignant lesions of the oral cavity. It serves as a marker for the detection of oral squamous cell carcinoma (OSCC). MCM2 overexpression also displays pro-apoptotic and apoptotic. MCM2 is also implicated in nonsyndromic hearing loss.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息