产品说明
一般描述
MMPs are a family of zinc-dependent endopeptidases that have functions in immunity and tissue repair. The activity of MMPs is strictly regulated by endogenous tissue inhibitors of MMPs.
免疫原
Synthetic peptide directed towards the N terminal region of human MMP10
应用
Anti-MMP10 antibody produced in rabbit is suitable for western blotting at a concentration of 2.5 μg/ml.
生化/生理作用
MMP10 (stromelysin 2) is an important moderator of migration and invasion of macrophages by the degradation of extracellular matrix. The activity of MMP10 produced by tumor cells maintains initiation and metastasis of tumor and is essential to maintain the stem cell-like properties of lung cancer cells.
序列
Synthetic peptide located within the following region: MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQ
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 54 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_002416 |
| UniProt登记号 | P09238 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MMP10(4319) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
