产品说明
一般描述
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity. IgA molecules in the serum are mostly dimeric. IgA is found in saliva, tracheobronchial secretions, genito urinary secretions, milk and colostrum. IgM is present on the surface of B lymphocytes in its monomeric form.
特异性
This product was prepared from polyspecific antiserum by immunoaffinity chromatography using antigens coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Goat Serum. No reaction was observed against Anti-Goat IgG F(c), Anti-Pepsin or Human Serum Proteins. This product is suitable for the detection of all Human immunoglobulin classes, isotypes and chain combinations.
免疫原
Mouse IgG IgA and IgM whole molecule
生化/生理作用
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. IgG2a of IgG has cytotropic properties and IgG2 molecules has the ability to activate complement.
物理属性
Antibody format: IgG F(ab′)2
外形
Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
重悬
Reconstitute with 1.0 mL deionized water (or equivalent).
法律信息
Texas Red is a registered trademark of Life Technologies
产品性质
质量水平 | 100 |
生物来源 | goat |
偶联物 | Texas Red® conjugate |
抗体形式 | affinity isolated antibody |
antibody product type | secondary antibodies |
克隆 | polyclonal |
形式 | lyophilized powder |
species reactivity | mouse |
technique(s) | direct immunofluorescence: suitable indirect ELISA: suitable indirect immunofluorescence: suitable |
运输 | wet ice |
储存温度 | 2-8℃ |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H302 - H311 - H411 |
预防措施声明 | P280 - P301 + P312 + P330 - P302 + P352 + P312 |
危险分类 | Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 |
补充剂危害 | EUH032 |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich