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位置:首页 > 品牌 > Sigma-Aldrich > Anti-Mouse IgG IgA IgM (H+L), highly cross adsorbed-Fluorescein antibody produced in goat

Anti-Mouse IgG IgA IgM (H+L), highly cross adsorbed-Fluorescein antibody produced in goat

品牌
Sigma-Aldrich
货号
SAB3701046
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
4069.14 *本价格含增值税费
促销
服务
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数量
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产品名称:
Anti-Mouse IgG IgA IgM (H+L), highly cross adsorbed-Fluorescein antibody produced in goat
FITC
产品介绍:

产品说明

一般描述

Immunoglobulin G (IgG) is a widely expressed serum antibody. It is part of the immunoglobulin family and consists of a gamma (γ) heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Immunoglobulin M (IgM) exists as a pentamer in the serum and has a high molecular weight. Monomeric IgM has a molecular weight of 190kDa. The pentameric IgM consists of ten μ-heavy chains, ten light chains and a single J-chain which is linked by disulphide bonds. The μ -chain consists of five domains- VH, Cμ1, Cμ2, Cμ3 and Cμ4. Immunoglobulin A (IgA) is found as two subclasses, that is, IgA1 and IgA2. IgA1 has an extended hinge because of the insertion of a duplicated stretch of amino acids, whereas IgA2 lacks this. IgA exists as a monomer or dimer in the secreted form. Dimeric IgA has a molecular weight of 390kDa. This antibody can form multimers and its polymerization is essential for transport across epithelia. IgA is crucial as the first line of defence and has an important role in mucosal immunity.

特异性

This product was prepared from polyspecific antiserum by immunoaffinity chromatography using antigens coupled to agarose beads followed by cross adsorptions to remove unwanted specificities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Fluorescein, Anti-Goat Serum, Mouse IgG, Mouse IgA and Mouse IgM. No reaction was obserbed against Bovine, Horse or Human Serum Proteins. This reagent is suitable for the detection of all Mouse isotypes and chain combinations.

免疫原

Mouse IgG IgA and IgM whole molecule

物理属性

Antibody format: IgG

外形

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

重悬

Reconstitute with 1.0 mL deionized water (or equivalent).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.46

产品性质

质量水平100
生物来源goat
偶联物fluorescein conjugate
抗体形式affinity isolated antibody
antibody product typesecondary antibodies
克隆polyclonal
形式lyophilized powder
species reactivitymouse
technique(s)direct immunofluorescence: suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable
运输wet ice
储存温度2-8℃

安全信息

象形图GHS06GHS09
警示用语:Danger
危险声明H302 - H311 - H411
预防措施声明P280 - P301 + P312 + P330 - P302 + P352 + P312
危险分类Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2
补充剂危害EUH032
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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