您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > Anti-MST3 (C-term) antibody produced in rabbit

Anti-MST3 (C-term) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300430
规格纯度
IgG fraction of antiserum, buffered aqueous solution
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-MST3 (C-term) antibody produced in rabbit
Anti-STE20-like kinase MST3
Anti-Serine/threonine protein kinase 24
Anti-Mammalian STE20-like protein kinase 3
Anti-STK3
Anti-STK24
产品介绍:

产品说明

一般描述

The yeast ‘Sterile 20′ gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM]
MST3 (mammalian sterile 20 (Ste20)-like kinase 3) gene is mapped to human chromosome 13q32.2. The gene is ubiquitously expressed in different tissues. MST3 belongs to the subfamily of the germinal centre kinase III kinases. It is also known as serine/threonine kinase 24 (STK24). The encoded protein contains a kinase domain and a regulatory domain at the N and C-terminal, respectively. The protein includes two isoforms namely MST3a and MST3b which differ by 12 amino acids. The protein is mostly localized in the cytoplasm.

免疫原

MST3 (Q9Y6E0, 350-384)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MST3.

生化/生理作用

MST3 (mammalian sterile 20 (Ste20)-like kinase 3) is known to be involved in the development of proper filopodia, dendritic spine, and excitatory synapse. MST3 induces outgrowth of axon and its regeneration in vivo. MST3 is associated with Caspase 3-mediated apoptosis in trophoblasts, induced by hypoxia.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号NP_003567
运输dry ice
储存温度−20℃
Gene Informationhuman ... MST3(8428)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品