Anti-MTFP1 antibody produced in rabbit

产品说明

一般描述

Mitochondrial fission process 1/mitochondrial 18 kDa protein (MTFP1/MTP18), a nuclear-encoded integral protein, is located in the mitochondria. It is also a phosphatidylinositol 3-kinase-dependent protein. MTP18 comprises three α-helical stretches or transmembrane (TM) domains of high hydrophobicity. The MTFP1 gene is located on human chromosome 22q12.2.

特异性

The antibody detects endogenous levels of total MTFP1 protein.

免疫原

Fusion protein corresponding to a region derived from internal residues of human mitochondrial fission process 1

应用

Anti-MTFP1 antibody produced in rabbit has been used in western blot (1:1000).

生化/生理作用

Mitochondrial fission process 1/mitochondrial 18 kDa protein (MTFP1/MTP18) controls mitochondrial fission Hence it helps to maintain the morphology of the mitochondria. Overexpression of MTP18 can facilitate fragmentation of the mitochondria. Loss-of-function of MTFP1 protein promotes cell death. It is crucial for cell viability.

特点和优势

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外形

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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