产品说明
一般描述
The gene STXBP1 (syntaxin binding protein 1) is mapped to human chromosome 9q34.1. The encoded protein is 594 amino acids long, which is expressed in all tissues with highest levels in retina and cerebellum.
Anti-MUNC-18A Antibody detects endogenous levels of total MUNC-18A protein.
免疫原
The antiserum was produced against synthesized peptide derived from human MUNC-18a.
Immunogen Range: 279-328
生化/生理作用
The gene STXBP1 (syntaxin binding protein 1) encodes a regulatory protein of the components of the SNARE (soluble NSF/ N-ethylmaleimide-sensitive factor attachment protein receptor) complex that are crucial for neurotransmission. It is a neuronal protein that functions in synaptic vesicle release. Mutations in this gene have been associated with early infantile epileptic encephalopathy. It causes autosomal dominant mental retardation and nonsyndromic epilepsy.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 67 kDa |
species reactivity | human, rat, mouse |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:40000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
NCBI登记号 | P61764 |
UniProt登记号 | P61764 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... STXBP1(6812) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich