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Anti-Myosin-VI Antibody

品牌
Sigma-Aldrich
货号
ABT42
规格纯度
from rabbit, purified by affinity chromatography
参考价格
5854.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Myosin-VI Antibody
Myosin-VI, Unconventional myosin-6
产品介绍:

产品说明

一般描述

Myosin-VI has been found in the membrane ruffles at the leading edge of the Golgi complex. Myosin-VI moves along the actin in the opposite way of other known myosins to date, toward the minus end. It can exist as a dimer and a monomer and is thought to function as a non-processive motor with a 18nm working stroke. Myosin-VI has also been found in the brain, specifically the synapses. Myosin-VI deficiency (Snell’s waltzer disease) in the hippocampus causes a smaller number of synapses, short dendritic spines and astrogliosis. Myosin-VI may also be important in clathrin-mediated endocytosis of acid-type glutamate receptors. Recent research has implicated myosin-VI in the enrichment of proteins on the surface of axons.

免疫原

KLH-conjugated linear peptide corresponding to human Myosin-VI.

应用

Immunocytochemistry analysis: A 1:500 dilution from a representative lot detected Myosin-VI in NIH/3T3 and A431 cells.
Research Category
Cell Structure
Anti-Myosin-VI Antibody detects level of Myosin-VI & has been published & validated for use in WB & IC.
Research Sub Category
Cytoskeleton

质量

Evaluated by Western Blot in MDCK cell lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Myosin-VI in 10 µg of MDCK cell lysate.

目标描述

~150 kDa observed.
An uncharacterized band appears at ~55 kDa in some lysates.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
MDCK cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivitymouse, human, canine
species reactivity (predicted by homology)rat (based on 100% sequence homology)
technique(s)immunocytochemistry: suitable
western blot: suitable
NCBI登记号NP_004990
UniProt登记号Q9UM54
运输wet ice
Gene Informationhuman ... MYO6(4646)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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