Anti-NEFM antibody produced in goat

产品说明

一般描述

NEFM (neurofilament, medium polypeptide) is a highly available cytoskeleton intermediate filament (IF) protein in post-mitotic neurons. It is mapped to human chromosome 8q21. It is abundantly present in the nervous system. In human, the protein has 13 carboxy-terminal domains with phosphorylation sites.

免疫原

Peptide with sequence CQASHITVERKDYLK, from the internal region of the protein sequence according to NP_005373.2; NP_001099011.1.

应用

Anti-NEFM antibody produced in goat is suitable for indirect ELISA and western blot analysis.

生化/生理作用

NEFM (neurofilament, medium polypeptide) protein is involved in the axonal transport and neuronal cell apoptosis. Phosphorylation of NEFM allows the association between NEFM and microtubules. Deregulated phosphorylation of NEFM is associated with Alzheimer disease (AD). From gene mutation analysis, it has been predicted that NEFM may be a susceptibility factor for the Parkinson′s disease (PD).

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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