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Anti-NEK7 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4500475
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-NEK7 antibody produced in rabbit
Serine/threonine-protein kinase Nek7
NimA-related protein kinase 7
NEK7
产品介绍:

产品说明

一般描述

NIMA-related Kinase 7/never in mitosis A-related kinase 7 (NEK7), a serine/threonine kinase belongs to the NIMA-related protein kinase (NEK) family. It is the smallest NIMA-related kinase (NEK) protein seen in mammals, which is made up of a catalytic domain with a 30–40 amino acid N-terminal extension. NEK7 is abundantly expressed in the heart, liver, testis, lung, muscle, brain, spleen, and leukocyte. The NEK7 gene is located on human chromosome 1.

免疫原

The antiserum was produced against synthesized peptide derived from human NEK7.

Immunogen Range: 101-150

生化/生理作用

NIMA-related Kinase 7/never in mitosis A-related kinase 7 (NEK7) is essential to form procentriole. It participates in regulating the cell cycle. In addition to the pathological and physiological effects, NEK7 is also involved in the formation of the spindle during mitosis. It is expressed at a high level in gallbladder cancer. NEK7 controls cytokinesis and stability of the microtubule. It can activate the spindle assembly checkpoint. NEK7 might also be associated with hepatocellular carcinoma (HCC).

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 34 kDa
species reactivitymouse, human
浓度~1 mg/mL
technique(s)ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号Q8TDX7
UniProt登记号Q8TDX7
运输wet ice
储存温度−20℃
Gene Informationhuman ... NEK7(140609)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg

Sigma-Aldrich

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