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Anti-NF-κB p105 antibody produced in rabbit

NF-κ-B1 p84/NF-κ-B1 p98

品牌
Sigma-Aldrich
货号
SAB4501990
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-NF-κB p105 antibody produced in rabbit
EBP-1
NF-κ-B1 p84/NF-κ-B1 p98
NFKB1
DNA-binding factor KBF1
NFkB-p50
产品介绍:

产品说明

一般描述

The gene NFκB1(nuclear factor κ B subunit 1) is mapped to human chromosome 4q24. It codes for κB p105/p50 isoforms.
Anti-NF-κB p105 Antibody detects endogenous levels of total NF-κB p105 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human NF-kappaB p105/p50.

Immunogen Range: 860-909

生化/生理作用

NF-κB (nuclear factor κ B) is an important transcription factor that regulates the process of apoptosis, immune response and cell-growth control genes. It is associated with a number of human disorders including inflammatory diseases and cancers. NF-κB signaling cascade is known to be stimulated by many genotoxic stresses and also DNA damage. NF-κB is involved in bone metabolism. Downregulation of NF-κB mediates GPER (G-protein coupled estrogen receptor) specific agonist G-1 induced EMT (epithelial mesenchymal transition) suppression. Thereby, it prevents the motility of triple-negative breast cancer cells in vitro.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 105 kDa
species reactivityhuman
浓度~1 mg/mL
technique(s)ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号P19838
UniProt登记号P19838
运输wet ice
储存温度−20℃
Gene Informationhuman ... NFKB1(4790)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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