Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody, clone 7.1

产品说明

特异性

NG2 (chondroitin sulfate proteoglycan), human which is the homologue of the rat NG2 molecule. The antibody reacts with a 220-240 kD surface protein whose N-terminal sequence is identical to the rat NG2 chondrotin sulfate proteoglycan molecule.

MAB5520 reacts with only neoplastic leukocytes with specific association with chromosome 11q23 translocations involving the MLL gene. It has a very high specificity for t(4;11) or t(11;19) translocations. The antibody shows no reactivity with normal marrow hematopoietic cells, peripheral blld leukocytes, red blood cells or platelets. Leukemic cells lines KG1, KG1a, HRL, Jurkat, K562, Raji, HL-60, U937, Daudi, Nalm6 and CEM are negative. However MAB5520 does react with a variety of cell lines of nonhematopoietic origin, including HeLa cells.

免疫原

Human bone marrow stromal cell line, SV40 transformed.

应用

Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody, clone 7.1 is an antibody against NG2 Chondroitin Sulfate Proteoglycan for use in FC & WB.
Western blot

Flow cytometry

Optimal working dilutions must be determined by end user.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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