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Anti-NOTCH2 (Cleaved-Ala1734) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4502021
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-NOTCH2 (Cleaved-Ala1734) antibody produced in rabbit
NOTCH2
NOTC2
Motch B
Neurogenic locus notch homolog protein 2 precursor
NTC2
产品介绍:

产品说明

一般描述

The NOTCH2 (notch 2) gene is mapped to human chromosome 1p12. Anti-NOTCH2 (cleaved-Ala1734) antibody detects endogenous levels of fragment of activated NOTCH2 (cleaved-Ala1734) protein.

免疫原

The antiserum was produced against synthesized peptide derived from human NOTCH2.

Immunogen Range: 1715-1764

生化/生理作用

The NOTCH2 (notch2) gene is known to be involved in the proliferation and cell cycle progression in cancer cells. Upregulation of the gene is observed in salivary adenoid cystic carcinoma, and hepatocellular carcinoma. Deletion of NOTCH2 offers tumor cells resistance to chemotherapeutic agents such as 5-fluorouracil. NOTCH2 plays an important role in the regulation of liver development. The NOTCH2 gene is associated with the development of diabetic nephropathy.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 79 kDa
species reactivityhuman, mouse, rat
浓度~1 mg/mL
technique(s)ELISA: 1:10000
western blot: 1:500-1:1000
NCBI登记号Q04721
UniProt登记号Q04721
运输wet ice
储存温度−20℃
Gene Informationhuman ... NOTCH2(4853)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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