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Anti-Noxa BH3 Domain antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300049
规格纯度
IgG fraction of antiserum, buffered aqueous solution
参考价格
4618.16 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Noxa BH3 Domain antibody produced in rabbit
Anti-PMA-induced protein 1
Anti-Immediate-early-response protein APR
Anti-PMAIP1, phorbol-12-myristate-13-acetate-induced protein 1
Anti-PMAIP1
产品介绍:

产品说明

一般描述

The expression of the Noxa gene, a BH3 only member of the Bcl2 family, involves direct activation of its promoter by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53 deficient thymocytes. Co-immunoprecipitation data suggests that Noxa protein may interact with proteins belonging to the Bcl2 family, such as, BclXL and Mcl1. Blocking endogenous Noxa induction results in the suppression of apoptosis. Treatment of cells with Noxa antisense oligonucleotides blocks radiation induced apoptosis, suggesting that Noxa may mediate p53 dependent apoptosis.

免疫原

NOXA (NP_066950, 12-52)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region (BH3 domain) of human Noxa.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: 1:1000
NCBI登记号NP_066950
UniProt登记号Q13794
运输dry ice
储存温度−20℃
Gene Informationhuman ... NOXA(5366)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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