产品说明
一般描述
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human Occludin (NP_002529.1).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 23 31 52 54 59 8 |
| species reactivity | rat, human, mouse |
| 浓度 | 1.77 mg/ml |
| technique(s) | immunofluorescence: 1:50-1:100 immunohistochemistry: 1:50-1:200 western blot: 1:1000-1:2000 |
| UniProt登记号 | Q16625 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... OCLN(100506658) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
Sigma-Aldrich
m.cnreagent.com
