Anti-OPRM1 (Ab-375) antibody produced in rabbit

产品说明

一般描述

The gene OPRM1 (opioid receptor μ 1) is mapped to human chromosome 6q24-q25. The gene spans a length of 200kb and contains 11 exons that yield 17 splice variants.

免疫原

Peptide sequence around aa. 373-377 (H-P-S-T-A), according to the protein OPRM1.

应用

Anti-OPRM1 (Ab-375) antibody produced in rabbit has been used in Western blotting.

生化/生理作用

The gene OPRM1 (opioid receptor μ 1) encodes a μ opioid receptor that functions in pain perception and addiction to drugs of abuse, such as cocaine, nicotine and alcohol. It serves as a target for opioid drugs, such as morphine, methadone and heroin and opioid peptides (like β - endorphin and endomorphins) and mediates their effects. Single nucleotide polymorphism in the OPRM1 gene is associated with an inclination to drug addiction and lesser response to painful stimuli.

特点和优势

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目标描述

Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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