产品说明
一般描述
Anti-Opsin antibody, Mouse monoclonal (rhodopsin) (mouse IgG1 isotype) is derived from the RET-P1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/C mice immunized with rat retinal membranes. Opsin is also called as rhodopsin protein, members of the G-protein coupled receptor (GPCR) superfamily. Opsin comprises >95% of the rod outer segments (ROS) intrinsic membrane and consists of a protein moiety - an opsin - and a non-protein moiety - the chromophore retinal.
应用
Anti-Opsin antibody has been used in
生化/生理作用
Opsin is an essential molecules for mediating the ability of animals to detect and use light for diverse biological functions. Mutations in the opsin (rhodopsin) gene are linked to retinitis pigmentosa (RP), a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness.
其他说明
rat retinal membranes
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | RET-P1, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~39 kDa |
| species reactivity | rabbit, turtle, fish, amphibian, human, avian, rat, mouse, bovine |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: suitable immunoblotting: 2-4 μg/mL using human retinoblastoma Y79 cell line extract. immunofluorescence: suitable immunohistochemistry: 5-10 μg/mL using rat eye frozen sections. radioimmunoassay: suitable |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P08100 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | rat ... Rho(24717) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
