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Anti-P21 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700189
包装型号
规格纯度
参考价格
4713.83 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-P21 antibody produced in rabbit
SDI1
CDKN1
WAF1
CDKN1A
MDA-6
CAP20
CIP1
p21CIP1
P21
产品介绍:

产品说明

一般描述

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human P21 (NP_001207707.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 18
species reactivityhuman, rat, mouse
浓度3.73 mg/ml
technique(s)western blot: 1:20-1:100
UniProt登记号P38936
运输wet ice
储存温度−20℃
Gene Informationhuman ... CDKN1A(1026)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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