Anti-PAX6 antibody produced in mouse

产品说明

一般描述

The paired box 6 (PAX6) gene with 14 exons, is mapped to human chromosome 11p13. The encoded protein belongs to the paired-domain Pax family. PAX6 is a 422 amino acids protein, generally expressed in the developing eye, both in neuroectoderm and surface ectoderm. It is also present in the adult eye.

免疫原

PAX6 (NP_000271.1, 1 a.a. ~ 422 a.a) full-length human protein.

Sequence
MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ

生化/生理作用

Paired box 6 (PAX6) is a highly conserved transcriptional regulator involved in oculogenesis. In addition, it is also implicated in maintenance of adult eye. Mutation in the gene leads to the development of aniridia in humans and small eyes in rats.

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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