产品说明
一般描述
PAX-5 is a B cell specificactivator protein (BSAP). In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20. PAX-5 is expressed primarily inpro-, pre-, and mature B cells, but not in plasma cells. Interestingly, PAX-5 mRNA is transiently detected in the mesencephalon and spinal cord during embryogenesis. Expression then shifts to the fetal liver and correlates with the onset of B lymphopoiesis. This indicates that PAX-5 is important in B cell development, but may also have a role in proper neuronal development.
免疫原
Synthetic peptide derived from C-terminus of human PAX-5 protein.
特点和优势
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外形
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
重组 | expressed in proprietary host |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | SP34, monoclonal |
species reactivity | human (tested) |
species reactivity (predicted by homology) | chicken, mouse, dog |
technique(s) | flow cytometry: 1:100 immunohistochemistry: 1:50 |
同位素/亚型 | IgG |
UniProt登记号 | Q02548 |
运输 | wet ice |
储存温度 | 2-8℃ |
Gene Information | human ... PAX5(5079) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich