Anti-PD-L2 Antibody

产品说明

一般描述

Programmed cell death ligand 2 (PD-L2, PD-1 ligand 2, PDCD1 ligand 2), also known as Butyrophilin B7-DC (B7-DC), is a member of the BTN/MOG family and immunoglobulin superfamily which is thought to act as a negative regulator of T cell activation. PD-L2 may play a role in stimulating an immunogenic response through an alternative receptor from PD-1. PD-L2 is highly expressed in heart, placenta, pancreas, lung, and liver and weakly expressed in spleen, lymph nodes, and thymus.

特异性

This antibody only recognizes the largest isoform at ~31 kDa.

免疫原

KLH-conjugated linear peptide corresponding to human PD-L2.

应用

Research Sub Category
Apoptosis - Additional
Anti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PD-L2 in mouse brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected PD-L2 in mouse brain cells.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in Raji cell lysate

Western Blotting Analysis: 2 µg/mL of this antibody detected PD-L2 in 15 µg of Raji cell lysate.

目标描述

~31 kDa observed. Uniprot describes 2 isoforms at ~21 kDa and one isoform at ~31 kDa Uncharacterized bands may appear in some lysate(s).

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Raji cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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