产品说明
一般描述
Peroxisomal membrane protein 13 (PEX13) is a component of the peroxisomal translocation machinery, which binds to peroxisomal targeting signal receptors via its SH3 domain, and facilitates the import of these receptors into the peroxisome membrane. Defects in PEX13 have been linked to neurodegenerative disorders, such as Zellweger syndrome.
免疫原
Recombinant protein corresponding to human PEX13 (peroxisomal membrane marker 13).
应用
Research Sub Category
Inflammation & Autoimmune Mechanisms
This Anti-PEX13 (peroxisomal membrane marker) Antibody is validated for use in Western Blotting, ICC for the detection of PEX13 (peroxisomal membrane marker).
Research Category
Inflammation & Immunology
质量
Evaluated by Western Blot in HepG2 cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected PEX13 (peroxisomal membrane marker) in HepG2 cell lysate.
目标描述
~49 kDa observed. This protein has an expected molecular weight of 44 kDa; however, it has been observed at ~49 kDa (Muller, C. C., et al. 2011. Dis Model Mech. 4(1):104-110.). An uncharacterized band may be observed at ~41 kDa in some cell lysates.
外形
Rabbit polyclonal serum with 0.05% sodium azide.
Unpurified
储存及稳定性
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
分析说明
Control
HepG2 cell lysate
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | serum |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | rat, human, mouse |
technique(s) | western blot: suitable |
NCBI登记号 | NP_002609.1 |
UniProt登记号 | Q92968 |
运输 | wet ice |
Gene Information | human ... PEX13(5194) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
Sigma-Aldrich