产品说明
一般描述
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer′s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
免疫原
A phospho specific peptide corresponding to residues surrounding S129 of human alpha-Synuclein
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | human |
| 浓度 | 1.35 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt登记号 | P37840 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SNCA(6622) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
