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Anti-phospho-ATM (pSer1981) antibody produced in rabbit

抗-磷酸化-ATM (pSer1981) 兔抗

品牌
Sigma-Aldrich
货号
SAB4300100
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-phospho-ATM (pSer1981) antibody produced in rabbit
Anti-ATA antibody produced in rabbit
Anti-AT1 antibody produced in rabbit
Anti-ataxia telangiectasia mutated antibody produced in rabbit
Anti-ATD antibody produced in rabbit
Anti-ATC antibody produced in rabbit
抗-磷酸化-ATM (pSer1981) 兔抗
产品介绍:

产品说明

免疫原

Peptide sequence around phosphorylation site of serine 1981 (E-G-S(p)-Q-S), according to the protein ATM.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cyclecheckpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins,including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNArepair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cellcycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. Two transcriptvariants encoding different isoforms have been found for this gene.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01321727
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 ~350 kDa
species reactivityhuman
浓度1 mg/mL
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
同位素/亚型IgG
免疫原序列(E-G-SP-Q-S)
NCBI登记号NP_000042.3
UniProt登记号Q13315
运输wet ice
储存温度−20℃
Gene Informationhuman ... ATM(472)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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