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Anti-Phospho-BCR-Y177 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700429
包装型号
规格纯度
参考价格
4713.83 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Phospho-BCR-Y177 antibody produced in rabbit
BCR1
PHL
CML
D22S662
BCR
ALL
D22S11
产品介绍:

产品说明

一般描述

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

免疫原

A synthetic phosphorylated peptide around Y177 of human BCR (NP_004318.3).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 137
142
species reactivityhuman, mouse
浓度2.66 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt登记号P11274
运输wet ice
储存温度−20℃
Gene Informationhuman ... BCR(613)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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