产品说明
一般描述
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
免疫原
A synthetic phosphorylated peptide around T186 of human CDK9 (NP_001252.1).
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | mouse, rat, human |
浓度 | 1.64 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt登记号 | P50750 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... CDK9(1025) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich