产品说明
一般描述
The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
免疫原
A phospho synthetic peptide corresponding to residues surrounding S291 of Mouse CGAS.
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | rat, human |
浓度 | 0.439 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt登记号 | Q8C6L5 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | mouse ... CGAS(214763) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich