产品说明
免疫原
Peptide sequence around phosphorylation site of serine 197 (A-A-S(p)-M-D), according to the protein FOXO4.
特点和优势
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目标描述
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
| MDL编号 | MFCD03791410 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~65 kDa |
| species reactivity | mouse, rat, human |
| 浓度 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (A-A-SP-M-D) |
| NCBI登记号 | NP_001164402.1 |
| UniProt登记号 | P98177 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FOXO4(4303) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
