产品说明
免疫原
Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V), according to the protein HDAC8.
特点和优势
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目标描述
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
| MDL编号 | MFCD02686596 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~42 kDa |
| species reactivity | human |
| 浓度 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (R-A-SP-M-V) |
| NCBI登记号 | NP_001159890.1 |
| UniProt登记号 | Q9BY41 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HDAC8(55869) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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