产品说明
一般描述
The heat shock transcription factor 1 (HSF1) gene is a member of the vertebrate HSF transactivators. This gene codes for an orthologous protein found across the eukaryotic phyla. It is present in the cytoplasm. HSF1 is located on human chromosome 8q24.
免疫原
The antiserum was produced against synthesized peptide derived from human HSF1 around the phosphorylation site of Ser303.
Immunogen Range: 270-319
生化/生理作用
The heat shock transcription factor 1 (HSF1) plays a major role in tumorigenesis, angiogenesis, invasion and metastasis. This protein participates in the development of hepatocellular carcinoma and induction of a CSC-like phenotype in breast cancer cells. HSF1 also supervises the structural integrity of the proteome.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 57 kDa |
| species reactivity | human, mouse, rat |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI登记号 | Q00613 |
| UniProt登记号 | Q00613 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HSF1(3297) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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