产品说明

一般描述

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

免疫原

A synthetic phosphorylated peptide around S32/S36 of human IκBα.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

产品性质

安全信息