产品说明
一般描述
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
免疫原
A synthetic phosphorylated peptide around S276 of human NF-kB p65 (NP_068810.3).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 58 59 60 |
species reactivity | mouse, rat, human |
浓度 | 0.95mg/ml |
technique(s) | immunofluorescence: 1:20-1:50 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:2000 |
UniProt登记号 | Q04206 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... RELA(5970) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich